A small setback. The food and water will last into the next spring, no worries, mate.

Unmanned Orbital Sciences Antares rocket explodes on liftoff (with supplies to ISS):

It's not clear what caused the explosive failure, but some have already pointed out that Orbital is using AeroJet Rocketdyne AJ-26 engines for its first stage. According to Spaceflight Insider, those rockets were built over 40 years ago in Russia before being imported, refurbished and upgraded for use with Antares.