刚才检索了一下可能性非常大:
For BRCA carriers, the OR associated with a 35 pounds weight gain after the age of 18 was found to be 4.64 (95% CI = 1.52–14.12; PTrend = 0.011) compared to those who gained less than 12 lbs.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670199/