Hammond的孪生子实验数据图在此
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送交者: wasguru 于 2007-05-01, 09:12:14:
这个图上近视和远视的数据是混在一起的。正数表示远视,负数表示近视。
仅对该图而言,至少有两个问题:一、同卵双胞胎远视的相关性远高于近视的相关性。Hammond是把整套数据放在一起分析的。如果仅分离出近视部分的数据(小于0的部分)来分析(但不要做二值化),表现出来的遗传率会低得多。二、有一对极端高度近视的同卵双胞胎(-9D/-10.5D),这一点数据可以使同卵双胞胎的相关性高出很多。如果没有这一点数据,表现出来的遗传率也会降低。
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他们应该列出了误差或者CI, it would good to see how much is the CI. (无内容)
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Latino2
(0 bytes)
2007-05-01, 12:53:29
(138421)
They did
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wasguru
(343 bytes)
2007-05-01, 13:10:57
(138427)
There is substential amount of inflation.
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Latino2
(280 bytes)
2007-05-01, 13:44:13
(138444)
Your guestimate makes more sense to me.
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wasguru
(68 bytes)
2007-05-01, 14:06:39
(138453)
Thanks.
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Latino2
(5 bytes)
2007-05-01, 13:32:50
(138438)
如果双胞胎小时候是分开的,那确实是个问题
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eng
(361 bytes)
2007-05-01, 11:20:55
(138398)
从统计学的角度看,作者的数据分析也存在问题
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wasguru
(605 bytes)
2007-05-01, 10:53:58
(138380)
另外,实验的对象是中老年人
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wasguru
(205 bytes)
2007-05-01, 10:09:43
(138369)
Is this graph for identical twins? (无内容)
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mangolasi
(0 bytes)
2007-05-01, 10:03:38
(138364)
There are two plots here
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wasguru
(22 bytes)
2007-05-01, 10:07:55
(138368)
It "looks" like a structural break to me... (无内容)
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mangolasi
(0 bytes)
2007-05-01, 10:18:56
(138372)
fraternal or dizygotic (DZ) and identical or monozygotic (MZ) (无内容)
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Enlighten
(0 bytes)
2007-05-01, 10:07:45
(138367)
远视和近视是不是同组基因表达的?有人知道吗?
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sam
(66 bytes)
2007-05-01, 10:02:22
(138363)
我不知道他们是否由同组基因控制
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wasguru
(60 bytes)
2007-05-01, 11:02:52
(138386)
Is this the British or Danish study cited by Fang?
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Enlighten
(195 bytes)
2007-05-01, 09:33:52
(138357)
It's the British study
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wasguru
(207 bytes)
2007-05-01, 09:38:35
(138359)
What do you mean by "binary"? Aren't the degree of myopia
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Enlighten
(51 bytes)
2007-05-01, 09:57:42
(138362)
binary means yes and no
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wasguru
(123 bytes)
2007-05-01, 10:06:24
(138366)
so they didnt directly use the data shown on the chart
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Enlighten
(193 bytes)
2007-05-01, 10:13:06
(138370)
wasguru, Does turning continuous data into binary data
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Enlighten
(324 bytes)
2007-05-01, 10:39:32
(138374)
The point is...
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wasguru
(164 bytes)
2007-05-01, 10:43:57
(138376)
when the pair(-9D/-10.5D) is transformed into binary
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Enlighten
(67 bytes)
2007-05-01, 10:43:21
(138375)
I meant this pair doesn't 使同卵双胞胎的相关性高出很多
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Enlighten
(28 bytes)
2007-05-01, 10:53:03
(138379)
They did't do threshold when they analyzed the overall refractive error
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wasguru
(293 bytes)
2007-05-01, 10:59:06
(138383)
I see. What a mess! (无内容)
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Enlighten
(0 bytes)
2007-05-01, 11:02:08
(138385)
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