◇◇新语丝(www.xys.org)(xys.dxiong.com)(xys.3322.org)(xys.freedns.us)◇◇

韩忠朝在血研所发表的第一篇论文系自我抄袭

camspumc

　韩忠朝教授这件事已经持续好长时间了，前几天看到血研所几位教授的事，非
常震惊。居然能让公安局去查电脑，太绝了。

现在让我们看一下韩忠朝教授在血研所发表的第一篇非综述论文，这是在“中华
血液学杂志 1999年第1期第20卷”收稿日期为1997-05-05，血小板第4因子及四
肽AcSDKP的造血保护作用研究，韩忠朝　蔡英林　S Aidoudi　JP Caen(论文1)。
(http: 
//www.37c.com.cn/literature/analecta/data/zhxyxzz/199901/010.html)。而
韩教授于 97年3月才开始来血研所，8月才正式就任。3月份时韩教授没有自己的
实验室，没有自己的实验人员，哪来的实验结果。其实很简单就是韩教授把其在
法国已发表的工作翻译后，经更改作者后又发表了。那篇原始论文发表在Br J 
Haematol. 1996 Sep;94(3):443-8，Aidoudi S, Guigon M, Lebeurier I, Caen 
JP, Han ZC.(Institut des Vaisseaux et du Sang, Hopital Lariboisiere, 
Paris, France)(论文2).

1。先看一下这两篇文章摘要：
论文1：
The hemoprotective effect of platelet factor 4 (PF4) and tetrapeptide 
AcSDKP　HAN Zhongchao, CAI Yinglin, S Aidoudi, et al.The State Key 
Laboratory of Experimental Hematology, Institute of Hematology, CAMS 
and PUMC, Tianjin　300020
　　【Abstract】　Objective　To study the effects of platelet factor 
4(PF4) and tetrapeptide N-acetyl-Ser-Asp-Lys-Pro(AcSDKP) on 
hemopoietic progenitors in mice treated with 5-Fluorouracil (5-FU). 
Methods　 Mice were injected with PF4 (40μg/kg) or AcSDKP (4μg/kg) 
twice at 6h intervals, and 20h after the second injection they were 
given one injection of 5-FU (150mg/kg),and the high proliferative 
potential-colony forming cell (HPP-CFC), burst-forming unit erythroid 
(BFU-E), colony forming unit megakaryocyte (CFU-MK), and megakaryocyte 
(MK) were examined 6,8 and 13 days later. Results　 The administration 
of PF4 or AcSDKP resulted in a significant increase of the number of 
HPP-CFC on days 6～8 and BFU-E and CFU-GM on day 8 when compared to 
5-FU alone. Furthermore, PF4 was found to increase significantly the 
number of CFU-MK and MK on day 8, which was not observed with AcSDKP. 
Conclusion　 PF4 or AcSDKP accelerate the recovery in vivo of HPP-CFC, 
CFU-GM and BFU-E after 5-FU treatment but their effect may be 
different on megakaryocytic progenitors. Both molecules may have a 
hemoprotective effect against chemotherapeutic agents.
论文2：In vivo effect of platelet factor 4 (PF4) and tetrapeptide 
AcSDKP on haemopoiesis of mice treated with 5-fluorouracil.
Aidoudi S, Guigon M, Lebeurier I, Caen JP, Han ZC.
Institut des Vaisseaux et du Sang, Hopital Lariboisiere, Paris, France.
In vivo effects of platelet factor 4 (PF4) and tetrapeptide 
N-acetyl-Ser-Asp-Lys-Pro (AcSDKP) on haemopoietic progenitors were 
studied in mice treated with 5-fluorouracil (5-FU). The mice were 
injected with PF4 (40 micrograms/kg) or AcSDKP (4 micrograms/kg) twice 
at 6 h intervals, and 20 h after the second injection they were given 
one injection of 5-FU (150 mg/kg). 6, 8 and 13 d later the high 
proliferative potential-colony forming cell (HPP-CFC), burst-forming 
unit erythroid (BFU-E), colony forming unit granulocyte-macrophage 
(CFU-GM) colony forming unit megakaryocyte (CFU-MK), and 
megakaryocytes (MK) were examined. The results showed that the 
administration of PF4 or AcSKDP resulted in a significant increase in 
the number of HPP-CFC on days 6-8 and BFU-E and CFU-GM on day 8 when 
compared to 5-FU alone. Furthermore, PF4 was found to increase 
significantly the number of CFU-MK and MK on day 8, which was not 
observed with AcSDKP. However, both molecules had no obvious effect on 
peripheral blood cells. These data indicate that PF4 or AcSDKP 
accelerate the recovery in vivo of HPP-CFC, CFU-GM and BFU-E after 
5-FU treatment but their effect may be different on megakaryocytic 
progenitors and suggests that both molecules may have a 
haemoprotective effect against chemotherapeutic agents

2。论文1中的图一与论文2中的表一一致；论文1中的图2与论文2中的图1一致；
论文1中的图3，4与论文2中的图1一致(这个原因不知是37C网提供错误，或血液
学杂志的错误，或作者自己抄袭错误)但图注论文2中的图2，3一致；论文1中的
图5与论文2中的图4一致；论文1中的图6与论文2中的表2一致。

3。论文1与论文2不一致的地方是图表中的标准偏差，这个显然由於论文1中的图
不是自动生成的，而是人工画的。

可笑的是韩教授在自我抄袭的时候，还没忘记加上一个血研所的工作人员，即蔡
英林教授。但1997年5月的时候当时的蔡英林副教授根本不属於韩教授研究组的
成员。另外1997年5月的血研所从法国IFFA实验室买过BALB/c小鼠吗？

韩教授这种行为怎么解释？据说有关部门对韩教授的文章进行过调查，不知这篇
文章是否包括在内？

韩教授为何不倒呢？韩教授的博士导师是非常有名的，同门师兄师弟更是有名。
唉，算我小人了。

(XYS20040408)

◇◇新语丝(www.xys.org)(xys.dxiong.com)(xys.3322.org)(xys.freedns.us)◇◇